Saturday, August 31, 2019
Christianity and Islam Essay
Judaism is the Jewish religion. It is one of the oldest of the great world religions, and is the mother religion of both Christianity and Islam. Judaism was not founded by one towering personality, as were most other religions. Abraham and Moses are not regarded as founders. Abraham was the ââ¬Å"father of the Hebrew peopleâ⬠and Moses was the ââ¬Å"law-giverâ⬠. I had the chance to interview Gary Austein. This interview was done for me to know the idea or perspective of a believer regarding his faith in his religion and that concerns his spiritual life. During the interview I asked Gary Austein the important holidays and traditions of this religion. He answered ââ¬Å"The important holidays and tradition of Judaism are Yom Kippur. Rosh Hashana and the Passover. The holiest day in the Jewish calendar is Yom Kippur, the Day of Atonement. This day is set aside to repent for the sins of the previous year. It is a day when any adult who has been Bar/Bat Mitzvahââ¬â¢s (age 12-13) fasts and reflects on the past year and asks God for forgiveness. Rosh Hashana is the previous weeks and is the Jewish New Year. Passover is in the spring and it is a time when Jews cannot eat unleavened bread reflecting on the Israelites exodus from Egypt. â⬠When I asked him on how Judaism has shaped his life? And I quote ââ¬Å"Religion defines who I am as a person. I would say I am a Jew first and an American second, that is how important it is to me. My value and belief system is a product of my Jewish identity and upbringing. My adult life has brought my Judaism more into my life than ever as I now have a Jewish home, Jewish wife and child on the way. I also work at a Jewish Day School so I am always reminded of my Jewish identity as both my professional and personal life revolves around my religion. â⬠What are the challenges, if any, to practicing this particular religion? Jews throughout the world are always a target of anti-Semitism. This is a fact that they accepted and so with other families. It is scary that millions upon millions of people have been murdered because of their belief in Judaism. Between the Holocausts, pogroms in Russia, and terroristââ¬â¢s attacks, an astounding amount of Jews have died because of their belief. Society is not very conducive for an observant Jewish lifestyle; Jews are supposed to observe the Sabbath (Friday night to Saturday night) and are not supposed to drive, work, spend money, etc. A lot happens on the weekends so this is difficult. Also if you keep Kosher (Jewish dietary restrictions) it is difficult to eat out as the vast majority of food and restaurants are not kosher. What are the false impression people have about Judaism? People have much false impression about Judaism. A lack of understanding and acceptance has led to misconceptions, not only of Judaism, but throughout the world. People need to always remind themselves that both Christianity and Islam were born from Judaism. Both religions accept the Torah (the Jewish Bible, also referred to at the Old Testament) as the word of God and credit Judaism for the birth of their respective religions. If people are more aware of this people then maybe open to differences of people. Judaism has clung to a number of religious principles, how important are they to your belief and values? Judaism defines who a Jew is; they wear it as a badge of honor. For them it is amazing that time still honors traditions that are still practiced at present. Something like male circumcision is the oldest religious tradition in the world today. It is amazing that it has lasted for thousands of years. It shows the resiliency and the testament of the Jewish faith that they are able to continue throughout the generations. What events and figures have shaped the faith of Judaism? Judaism has greatly shaped his life as a Jew. And it is through the people around that have helped him a lot in his Religious belief. His parents gave him his Jewish identity and the friends of his family have nurtured it. His best friend who is a rabbinical student has been very influential in shaping his Jewish identity. His marriage also shaped his Jewish identity as his wife converted to Judaism which has given him a newfound zeal and love for his religion. His study of Holocaust has been a dramatic part of his Jewish identity. Finally his visits to Israel, the Jewish state has given him a unique pride in his homeland. There are many Jewish denominations. To want certain extent the philosophies of these movements have shaped the reaction to one another? He considers himself a Conservative Jew which is best classified as the middle of the road. For the most part, Jews of different backgrounds are fairly understanding and respectful of the traditions and practices of other sects of Judaism, with the exception of the ultra-Orthodox movement. He believes that if you are a Jewish according to the laws and traditions of Moses then it does not matter how you practice as long as you believe it in your heart. However, he believes that there are certain misinterpretations some of the other sects have undertaken, but that is not something that he could be worried or be burden about. Judaism has been the common bond of the Jewish people. It is the foundation of their culture and the reason for the creation of Israel, the Jewish State. Israel is the most important tangible asset they have and something that must be protected at all costs. Judaism is the reason the Jewish people have and are persecuted, yet is the belief and intangible asset that keeps them together as a people. According to Jewish tradition, the history of Judaism begins with the Covenant between God and Abraham. What is the Covenant? ââ¬Å"The Covenant is the ââ¬Å"agreementâ⬠between God and Abraham, the patriarch of the Jewish people, that the Jews will be ââ¬Å"the chosen people. â⬠This is a fact that is accepted by both Christians and Muslims alike. This covenant was symbolized by Abraham being circumcised and is something that is required for all Jewish males a week after they are bornâ⬠. Judaism is different from many religions, how does differ? He answered, ââ¬Å"This is a common misconception. All three of the major monotheistic religions, Judaism, Christianity, and Islam have more similarities than differences. Their major prophets are the same; their historical texts are born out of the Jewish Bible, and their belief in one all powerful, all knowing, and benevolent God is distinct commonalities. They all practice and worship God in different ways, but when it comes down to it, they were all born from Abraham and Sarah, meaning they are all brothers and sistersâ⬠. The interview taught me the importance of having respect for otherââ¬â¢s faith and beliefs. It is also important that any individual must know the values that the other people in the society portrays because that is how they were brought up with especially with regards to their religion. My experience during the interview was worth it, I learned a lot especially coming from a devoted person. What he shared to me were the same with the informationââ¬â¢s in the textbook we used in the class.
Friday, August 30, 2019
The Diagnostic and Statistical
People have their own personal faith and belief. Our cultural and parental upbringing influence our lifeââ¬â¢s principles and beliefs. We may encounter differences with other people based on views and perception on things. And these differences among people comprise the earthââ¬â¢s diversity. There are people who are intolerant of otherââ¬â¢s opinion and prejudice. They are also raged by other people belonging from a different race or ethnic background (ââ¬Å"Bigotâ⬠). They may also feel outraged by otherââ¬â¢s lifestyle and identities that are different from their own. Bigotry is the characteristic and attitude of a bigot.It is the corresponding mindset of people who are extremely judgmental other people. Bigot is a term used in describing people who are firmly devoted in their prejudices, especially when their views are threatened or challenged. It is used to refer to people who hold blindly and intolerantly of their personal creed, opinion and belief (Adamson 200 ). Bigot is often mistaken by people as prejudice. Most people are confused between the two words. Prejudice happens when we tend to easily judge someone or something based solely on our personal opinion or attitude. Prejudice is also a learned behavior.We are taught of what to think about people of different gender, race and disability. It is influenced by our parents and neighborhood. Bigotry is hate. It is a form of prejudice carried to an extreme manner (Martin 149). There are various kinds of bigotry such as religious, racial, political, national and cultural bigotry. Bigotry is most likely seen in aspects of religious and political field. Many people hold fanaticism in their religious and political views. Individuals and groups tend to be blindly deluded by the belief that their religion, race, political party, nation and culture are more superior than the others.Such beliefs made them blindly and intolerant of others (Adamson 200). Based on the canonical definition of psychop athology, it seems to apply on visceral bigotry. Bigotry is not considered as a sickness but it can be regarded as a dysfunction based on some influential definitions of psychopathology. The Diagnostic and Statistical Manual of Mental Disorders define mental disorders based on distress, disability and increase in harmful effects. Alvin Poussaint, a Harvard psychiatrist, believes that bigotry fits the definition and advocates in putting it on the list.Bigotry may be a dysfunction in responding to large segments of humanity. It may constitute impairment in responding healthy and responsible ways toward the targeted groups because of irrational hatred and contempt and other negative attitudes (Martin 130). If a person professes negative remarks blaming single mothers on the impairments of the society, it may be a form of bigotry. This may be under sexism or the belief that one judged the other based on their sex or gender and not through their capability as an individual. They believe that one sex is superior than the other.This is evident in the workplace environment where performance and capabilities are judged based on sex rather than having better qualifications. Sexism may also happen at home, school and society or community (ââ¬Å"Forms of Bigotryâ⬠). In the case of having blamed the single mothers for the social ills in the society implies many unverified perceptions toward our women, specifically our single mothers. Single mothers refer to women raising their children in the absence of the father or their husband. Being a single mother is never an easy task. They take on many difficulties in trying to raise their children while earning for a living.Single mothers do not have the aid of their husband either partially or totally. This may cause difficulty in their part. Bigots toward them may blame them for taking part on the national aid extended by the social welfare department. The government extends financial aid on poor families with unemployed h ead of the family. There are also shelters that welcome homeless individuals. Sexists may blame the single mothers for their incapability to find decent jobs and provide the needs of the children. They may also blame the single mothers if their children turned nuisance to society.The delinquency of the children is blamed on their mothers for their incapability to rear them appropriately to become good citizens of the society. If their children become problems of the society, mothers are on the line questioning their eligibility and capability as a mother. It does not question the single fathers trying to raise their children and earn a living at the same time assuming that single fathers can perform the two tasks flawlessly at the same time. This may be viewed as a bias for some women, who may do better than some single fathers.Some single fathers also may be involved in neglecting their children or other types of child maltreatment. It may be a form of bigotry for it generalized si ngle mothers as the culprit of social ills in the society. Being a sexist undermines the qualifications and abilities of people belonging on the other sex to take on a job or task. A sexist may view their sex as superior to others. They may view the other sex as inferior to them and not at their level. Viewing one sex as superior to other creates biases and prejudice toward the views on sex. Bigotry is involved when there is an extreme prejudice, hatred and contempt towards the other sex.Works Cited Adamson, Joseph J. What the World is Coming To?. Lincoln, NE: I Universe, Inc. , 2004. ââ¬Å"Bigotâ⬠. Merriam-Webster Online Dictionary. 2009. 26 January 2009 . ââ¬Å"Forms of Bigotryâ⬠. articleworld. org. 24 January 2006. 26 January 2009 . Martin, Mike W. From Morality to Mental Health: Virtue and Vice in a Therapeutic Culture. New York, NY: Oxford University Press, Inc. , 2006. Martin, Renee J. Practicing What We Teach: Confronting Diversity in Teacher Education. Albany, Ne w York: State University of New York, 1995.
Thursday, August 29, 2019
Can Companies Use Mentoring to Increase Employee Retention? Essay
All businesses, from an entrepreneurial start up to an established company, need mentoring. The entrepreneurs of those companies require mentoring as well. A mentor can help a fellow peer develop important business skills, support them in making important career and life decisions and put them in touch with needed network contacts. The purpose of my report is to analyze the results of putting a mentoring program in place in a company and why it can reap rewards for the employees and the organization. The key variable that I will be focusing on is employee retention since ââ¬Å"SHRM, the Society for Human Resource Management, estimated that it costs $3,500.00 to replace one $8.00 per hour employee when all costs ââ¬â recruiting, interviewing, hiring, training, reduced productivity, et cetera, were consideredâ⬠(Blake 2006). Imagine the cost to the company when considering a $40,000 a year corporate employee! (DegreeSearch.org) Mentoring can be an influential tool in familiarizing employees to an organizationââ¬â¢s culture and help them grow in their jobs. It can be tremendously valuable to have someone who has your best interests at heart and can explain the facts of your corporate culture and offer treasured advice. Informal mentoring has been going on continually, but companies are increasingly identifying that formal mentoring programs can provide momentous benefits for both the employee and the organization. Positive benefits include is statistical growth in employee retention, growth and satisfaction. The focus of my analysis was the increase in employee retention vs. Articles: Blake, Rose. Employee Retention: What Employee Turnover Really Costs Your Company. WebProNews. July 24, 2006. Bridgeford, Lydell. Mentoring Programs Still Have a Place in the 21st Century. Employee Benefit News, August 1, 2007 Corporate Leadership Council. (2005). Mentoring: From Theory to Action. Corporate Leadership Council, 18. DegreeSearch.org (2011), Mentors Make a Difference Infographic. Dunnett, R. (2012). Mentoring matters. Director (00123242), 65(6), 50-53. LESTER, P. B., HANNAH, S. T., HARMS, P. D., VOGELGESANG, G. R., & AVOLIO, B. J. (2011). Mentoring Impact on Leader Efficacy Development: A Field Experiment. Academy Of Management Learning & Education, 10(3), 409-429. Miloff, M., & Zachary, L. J. (2012). Mentoring to Develop Strategic Leaders. T+D, 66(4), 102-104. Offstein, E. H., Shah, A. J., & Gnyawali, D. R. (2011). Effects of CEO-BOD Mentoring on Firm Competitive Behavior. Review Of Business, 32(1), 75-88.
Wednesday, August 28, 2019
Small assignment Essay Example | Topics and Well Written Essays - 500 words
Small assignment - Essay Example At the end of the ongoing renovation and expansion process, which will be over within a week, I assure you we will have better services. We have tried our level best not to cause many inconveniences to you and decided that we can finish the installation of new equipment within 24 hours. I hope all the valued customers of ONELAB will understand the necessity of this closure and expect and request your cooperation. If you have any queries, please feel free to contact us either by mail or through phone As part of our expansion and renovation plans, we are all set to install some of the most modern equipment which is needed to increase our service capabilities. These machineries are quite new in the market and we believe that you need some training on this equipment before the reopening of the lab after the 24-hour closure, which will begin from tomorrow morning at 6 a.m. onwards. The training session on this equipment will be conducted tomorrow in order to avoid any time delay to the customers and I ask all our employees to report for training tomorrow at 6 a.m. even though the lab will remain closed for customers. As part of our expansion and renovation processes, we are all set to install some of the most modern equipment which is needed to increase our service capabilities. As a result we are forced to implement a 24-hour close down of our lab from 6 am tomorrow (10/9/09) to 6 am the day after tomorrow (11/9/09) and no deliveries or receipts will be executed during this period. I expect a big increase in the volume of our business after the renovation and expansion process which will definitely be beneficial to you as well. I request your cooperation and valued services in the future also. As part of our expansion and renovation plans, we are all set to install some of the most modern equipments which needed to increase our service
Labor Unions Essay Example | Topics and Well Written Essays - 750 words
Labor Unions - Essay Example Moreover there was a special department in the US Department of Labor, which took stock of strikes. Now labor unions comprise only 12 % of Americans, and only 8 % of those 12 % are the employees occupied in private sector. The main reason is a shift, which took place in the relationship between employers and workers. For centuries labor unions struggled for good conditions for employees. In contemporary world employees are in competition with each other in order to get a better job. American corporations long ago realized that it is more efficient to hire purposeful, responsible, and interested in their job people. Accordingly people, who get a job today, automatically receive all those privileges labor unions for had struggled for. Moreover, many corporations give their workers a possibility to become co-owners, offering them an opportunity to get low price stocks of the own enterprises. Thereby membership in labor unions for many Americans became senseless. As a matter of fact labor unions cannot find their place in the new system of labor relationship. In the course of time fundamental economic changes had happened in the country. The traditional heavy industry, a stronghold of labor unions, gradually becomes the thing of the past. According to Turner, 'if unions can not hold their own and adapt to changing circumstances in the core industrial work force, the traditional bastion of labor strength, it is difficult to imagine that national prospects for unions elsewhere can be promising1'. Labor unions also have not been taken in the extremely developing industry of high technologies, and have not been widely accepted in the services sphere. So we can agree with the statement of Robert Baldwin, who claims that one of the factors that contributes to weakling of labor unions is 'unskilled labor-displacing nature of new technology, including outsourcing2'.Notwithstanding it is wrong to say, that labor unions are doomed. One can hardly find an example of a democratic society, which does not have labor unions in its structure. American labor unions now are trying to take their own place in the new national economy. John Sweeney, the President of American Federation of Labor - Congress of Industrial Organizations, claimed that Georges Bush's administration carries out the worst labor unions policy in modern history. He stated that 'in the face of the most anti-worker Administration in decades, America's workers are struggling to get a leg up in this economy - - and many are trying to form unions3' Let us consider the example of Northwest Airlines. In 2005 for the first time almost for a quarter of a century in the main headings in the American press there was a word "strike". The company urged on by the competition with inexpensive young airline companies, wishing to save 176 million dollars, wanted to dismiss a part of the personnel. There have been almost 4,5 thousand workers of Northwest Airlines striking. By the threat of flights cancellation employees have been trying to achieve the fulfillment of the term of the contract by the leadership of the company the work in. However management has fought labor union back. It had prepared the replacement of striking employees in advance and has declared that the company would continue to carry out all the planned flights. The labor union of aircraft mechanics has not made concessions to the company. Negotiations have been
Tuesday, August 27, 2019
Late Roman, Early Christian and Byzantine Art Essay
Late Roman, Early Christian and Byzantine Art - Essay Example Galla Placidia passed on in Rome, and irrespective of a long custom to the contrary, it is nothing like she was ever buried in Ravenna. Most likely, she was laid to rest in the Rotunda of St. Petronilla. The Rotunda is acknowledged as to have been the mausoleum of the relatives of Theodosius, and Galla herself. Modern erudite opinion is that Mausoleum of Galla Placidia was constructed as a rhetoric rather than mausoleum. It was uniquely linked to the narthex of the close church of Santa Croce, which is recognized to have been constructed by Galla Placidia so she possibly bespoke the oratory, and it fittingly takes her name, though she was never laid to rest there. The mosaics of Galla Placidia have fascinated millions of visitors from across the world over the centuries (Stokstad 25) The mausoleum of the oratory features a beautiful mosaic of a glittery night sky. The stars over eight hundred of them are set in concentric orbits around a golden Latin cross, with the cryptograms of the Four Evangelists upon the spandrels. The arcs of the side niches have equivalent golden patterns upon a dark background, featuring an assortment of flowers and plants down with additional stars. Next, it is essential to consider that the cross on the catacomb is jutting toward the east instead of being united with the position of the Chapel. This is nearly surely since the Chapel is not aligned to the in harmony with the set up custom, and the decorator partly corrected that by offering the central cross the appropriate alignment. May be the most essential mosaic in the Mausoleum of Galla Placidia is an early illustration of Christ as the Good Shepherd, situated over the entry upon the north side. The image was common in the Roman vaults of earlier centuries, but there are essentia l advancements to be witnessed in his adaptation. As opposed as to being depicted as an atypical countryman, this Good Shepherd has a
Monday, August 26, 2019
The Current Evidence of Human Evolution (Human Biology essay) Essay
The Current Evidence of Human Evolution (Human Biology ) - Essay Example Unlike in the past, modern humans have created complex communal structures that are composed of many competing and cooperating groups, from individualsââ¬â¢ families to states. Social communications between humans also have established wide diversity of traditions, values, ethics, laws and social norms which all form human societyââ¬â¢s basis modern humans have showed a bigger appreciation for aesthetics and beauty which when joint with the wish for self-expression, it has led to modernizations like music, literature and art. Modern humans are largely distinguished for their numerous desires to comprehend and influence the earth in search of answers to of explaining and manipulating normal phenomena through religion, science, mythology and philosophy (Cremo, 2010, p.49). This curiosity is what has enhanced the development of skills and advanced tools; modern humans are the only species that are currently known to clothe themselves, cook their food, build fires, and develop and enhance other numerous technologies (Oââ¬â¢higgin &Cohn, 2000, p.89). This is unlike in the past where species dint use to light fires, eat healthy and nutritious food clothe t hemselves or know how to use any modern tools which shows that human beings have evolved over many years and are still evolving. Modern humans also pass their knowledge and skills to future generations through continuous education. Modern humans are genetically different from early human because of the increased rate of evolution which is as a result of increase growth of human population and their movements into new environments like cities, where most are taken as major subject to emerging natural collection pressures (Cunnanes & Stewart, 2010, p83). Evolution of human is characterized by various essential morphological, behavioral, physiological and developmental changes that have occurred since the split between chimpanzees and the last human beingââ¬â¢s ancestor. The
Sunday, August 25, 2019
Television Effects on Children Research Paper Example | Topics and Well Written Essays - 1750 words
Television Effects on Children - Research Paper Example ar I may have rode a horse to school and spent their days primarily taking care of the family farm or working in what would now be considered ââ¬Ësleepy hamletsââ¬â¢ with malt shops, drug stores and barbers sweeping their front step. Their children listened to the radio, rode in cars, could call anyplace in the world and enjoyed the comforts of electricity and indoor plumbing. While this lifestyle was already accelerated to at least twice the speed of their forebears, it was the next generation that was changed most by technology. In the 1950ââ¬â¢s, television entered the home becoming part of almost every family. It was not simply a tool; it entertained, educated and babysat the generations to follow. Society took its biggest leap either forward or backward, depending on your viewpoint, after the public adopted what was to become the family friend. Commentators have noted how each generation since the introduction of the television have become progressively more violent, le ss active and suffer from an increasingly diminished attention span. It seems reasonable, therefore, to look to the television as the possible source of this violence as it negatively affects the development of our children. Studies vary on the exact amount of television children watch per day but it is commonly accepted that it is a large percentage of their lives outside school and sleep. While mesmerized in front of the T.V., children are exposed to many hours of violence, drug use and sex as well as to influential, sophisticated and enticing commercials. Research regarding the behavioral outcomes of television advertising found that it is a significant factor in determining the specific items children request and contribute to childrenââ¬â¢s sense of social status based upon whether they can ââ¬Ëhave thatââ¬â¢ or not. From the time of televisionââ¬â¢s inception, no one has doubted that this medium would generate its operating revenues from advertising. However, advertising directed
Saturday, August 24, 2019
Applied Microbiology Essay Example | Topics and Well Written Essays - 1000 words
Applied Microbiology - Essay Example Additionally, the accessibility of the microbial genome sequences gives a wide scope of opportunities to understand as well as exploit the microorganisms present in the wine. The influence of molecular revolution in medicinal applications is evidenced by the genetic alteration of bacteria to produce an enzyme that can treat a human disease (Sehgal, 2012). For example, nanotechnology has led to the deliverance of the drug in different forms such as dendrimers, nanoshells and nanotubes to specific genes in humans (Sehgal, 2012). Development of synthetic neology will lead to the extensive application of applied microbiology in the production of biodegradable biomaterials. For instance, it is apparent that bioplastics will replace the production of non-degradable waste materials. In relation to this, microbes such as aerobes, anaerobes as well as photosynthetic bacteria with the ability to accumulate and catabolise polyesters responsible for the formation of bioplastics will be used (Garcia, Luengo, Naharro, Olivera & Sandoval, 2003). Additionally, it is evident that the development of synthetic neology will lead to the large-scale creation of recombinant organisms with the ability to synthesize bioplastics from cheap carbon sources. Apart from replacing non-biodegradable materials, synthetic neology will lead to the production of materials that will be used in the health sector (Garcia et al., 2003). For instance, the polyesters produced by the microorganisms will be used in medical applications like sutures , implants, and urological stents. In addition to this, the polyesters will be used in the treatment of narcolepsy as well as alcohol addiction. Biologic products are derived from natural (biological) products. They include medical products such as vaccines, blood products, and allergenic extracts such as allergy shots. A natural product, on the other hand, is a product of a
Friday, August 23, 2019
Online Marketing Essay Example | Topics and Well Written Essays - 2000 words - 1
Online Marketing - Essay Example One of the major companies that are currently practising online marketing and doing perfectly in the business is the coca cola company for soft and non-alcoholic drinks (Blum, Sandholm, & Zinkevich, 2002). Coca Cola Company is based in Atlanta, Georgia in United States under the management of Muhtar Kent. The company manufactures, retails, and markets non-alcoholic drinks all over the world. The company was launched by Griggs Candler in 1892 and has been in the business since then making tremendous steps and achieving great success (Hartogh, 2007). Coca Cola Company has been very successful in the market due to its quality drinks that differentiate its products from those produced by the competitors. The companyââ¬â¢s great success is not only attributed to quality products but also to recent advertisement techniques such as online marketing and other forms of advertisements such as social media. The companyââ¬â¢s high market penetration can be attributed to its ability to respond to customers taste and preferences depending on their geographic area. The company serves and distributes its drinks to over 200 countries all over the world currently. It has its headquarters in every country where bottling and distribution strategies take place (Ba, Whinston, & Zhang, 2003). Coca Cola being a giant company in the field of beverages has taken many steps in the business expansion. The best strategic decision taken by the business is online marketing. The company launched internet websites many years ago (Tian, 2006). Website plays a major role in the field of marketing by improving the relationship with the customers and better customer services. The company is currently running its website that can be accessed by using www.coca-cola.com. Apart from this website the company has several other websites depending on the country of interest. A website fulfils many purposes for an organisation. A website design serves as a
Thursday, August 22, 2019
Busy streets of London Essay Example for Free
Busy streets of London Essay Someone once told me that London was the most beautiful city they had ever seen. As I walked through the streets of London I couldnt help but see the ugly side. The people were shadows to me, the buildings loomed over like leering monsters and the car headlights reminded me of the eyes of wild beasts. Everybody was so unapproachable, I felt lost, and even though I was surrounded by a sea of people I still felt all alone. As night began to fall, darkness surrounded me. Even though the streets of London are vividly colored, the only colour I could see came from the cold smear of red buses. When you feel like an ant in a massive city you cant help but feel scared, especially at night. People spill out of pubs and bars onto the pavements, but they are still never empty. I had been walking along streets for hours trying to find a secluded spot to crash over night, it took a while but I finally found a potentially nice spot to snooze, a slightly worn path in a back alley full of emptiness. I had the creepy feeling that I was being watched, although I have no idea who by because Id never felt so alone. I put the thought to the back of my head and after minutes of twisting and turning I felt hidden enough to try and get some sleep. Within 5 minutes of shutting my eyes I heard a group of rowdy, drunken girls. I stayed as still as possible and none of the girls noticed me. Then about two minutes later I noticed a man walking his dog at the other end of the alley. As the dog came closer I could hear it sniffing and panting louder, my heart began to pound. I was ashamed of the situation I was in. I didnt want anyone seeing me, luckily the man called the dog over, it paused and ran to its owner, Good dog the man said. A while later it started rain, I stayed in the same spot in hope that the it would dye down, but it got harder and colder to the point where I couldnt feel my hands and my teeth couldnt stop chattering. I rubbed my arms up and down for about half an hour trying to keep warm, I breathed into my hands and curled up into a balled thinking that some how I would be warmer. The cold night made me think about the little things I took for granted at home like, warmth with the flick of a switch, the comfort of my own bed, the homely noises of my family that I was used to. All these things I missed so much, I cried for hours not knowing where to go or what to do. Instead of moving to a spot to find shelter from the rain, I gave up and eventually so did the rain. The next morning I was awoken by the sound of my own belly rumbling. Every time I moved I could hear the wet from the rain inside my clothes and shoes. As I looked around it seemed like the city had come to life all over again, waiting for the day ahead. Street lights going out as the sun rose up, but I still felt the same. Nothing had changed for me. Except one thing, I realized that for the best part of my life Ive spent my time not feeling like I belong, going from flat to flat, from bedrooms to floors and now to nothing but a cold pavement in an alley. No-where up until last night had been this bad, I just wanted to go home. So I picked up my belongings, which consisted of a tattered blanket that was big enough to cover a small child and a rusty old drink bottle, and set about finding my family. . .
Wednesday, August 21, 2019
Structural Theories Essay Example for Free
Structural Theories Essay Motives are believed to be the reason behind the action of people. Whether negative or positive, they are the cause of an individualââ¬â¢s action. Since motives help us better recognize why a person would do something, a lot of research has been committed to understanding the pattern of people or group of peoples motives. Knowledge of patterns is crucial to many aspects of human behavior but especially those relating to crime. Knowing a pattern helps one to predict, and hopefully help educate others on future crimes. The research of crime is so extensive that researchers have created not only theories but also various subculture theories of crime. Subculture theory of crime is a set of theories arguing that certain groups or subcultures in society have values and attitudes that are conducive to crime and violence. Subcultural theories of Cloward and Ohlin, Wolfgang and Feracuti, Elijah Anderson, and Walter Miller offer a great deal of insight on why different groups of people choose to engage in the crimes that they participate in. Although these theories are broad and shed light on what certain groups will attribute to crime, it is not an exact science. A lot of these theories come along with critiques that question the basic points the researchers are trying to prove. Cloward and Ohlin theorized illegitimate opportunity structures, which argues that in order for someone to obtain and take advantage of the most rewarding illegitimate opportunities, aspiring delinquents often need an ââ¬Å"inâ⬠. Within the illegitimate opportunity structure there are different subcultures and cub cultures. Cloward and Ohlin go on to split people into different subcultures of criminals who do not have an ââ¬Å"inâ⬠. The subcultures of the criminal structure that are offered are Conflict subculture, conflict gang, retreatist gang, and retreatist cub culture. Those who fit in Conflict subculture turn their frustration at failure in both the legitimate and illegitimate opportunity structures into violence and those that are in gangs aim to make money through a variety of illegitimate avenues. While conflict gangs engage in violent activities, doing whatever is necessary to maintain their status in the streets and finally retreatist gangs are considered ââ¬Å"double-failuresâ⬠no success in either legitimate or illegitimate opportunities turn to drugs. Some critiques to Cloward and Ohlin have been that they fail to realize that the different subcultures can overlap. For example, gangs involved in conflict subculture often deal in and use drugs, and make large sums of money in the process. Unlike Cloward, Ohlin, Wolfgang and Feracuti, Walter Miller argued that crime is simply an extension of normal working class values, not a distinctive set of alternative values. Miller argued that the lower classes create their different value system as a response to the monotony of working ââ¬âclass jobs and a life of poverty. Working-class subculture is a mechanism full of processes, which allow working-class people to cope with their situations. He termed this focal concern. These focal concerns are fate, autonomy, trouble, excitement, smartness, and toughness. Due to the fact that these characteristics can be distributed throughout society, Walter Millers theory is thought to be too fixated on working class values. His theory also has too much of a focus on boys. Wolfgang and Feracuti argue the subculture of violence; they believe that violence is a product of conformity to a pro-violent subculture that is in direct conflict with the dominant culture. They suggest that violent reactions to perceived threats to reputation or honor are culturally prescribed, given that a failure to react defensively may result in life-threatening consequences. These researchers even go on to apply this theory outside of disadvantaged neighborhoods, such as the American south, athletes, and postal workers. Still critiques feel as though Wolfgang and Feratuci infer the existence of subcultures of violence based on statistical indicators of high rates of violence in poor racialized neighborhoods. Another important critique is that not everyone follows the values and norms of violence. This critique was then explored in Andersonââ¬â¢s study. He revealed ââ¬Å"streetâ⬠and ââ¬Å"decentâ⬠value orientations among families in Philadelphia neighborhood. In Elijah Andersonââ¬â¢s ââ¬Å"code of the streetâ⬠he proposes that the highà rates of violence amongst inner-city residents can be attributed to a ââ¬Å"code of the streets.â⬠This code, he notes, functions as a ââ¬Å"set of informal rules governing interpersonal public behaviorâ⬠that encourages the use of violence for the purposes of maintaining honor and defending reputation. Just like Cloward and Ohlinââ¬â¢s Conflict gang subculture and Wolfgang and Fercutiââ¬â¢s subculture of violence, Anderson believes that crime occurred in certain neighborhoods in order to maintain status and respect. However new improvements on this contemporary theory were added when Anderson included the variations of families that lived within this pro-violent culture. He concluded that while both contingents experience the hardships of race and class oppression, ââ¬Å"rather than dwelling on the hardships and inequities facing them,â⬠Anderson argues, ââ¬Å"civilâ⠬ individuals tend to ââ¬Å"accept mainstream values more fully than ââ¬Å"street familiesâ⬠and make the best of what they have (Anderson, 1999: 38). Although this theory goes on to prove that not everyone in a pro-violent environment upholds the same values, it fails to clarify the specific processes that had led the residents of Germantown Avenueââ¬â¢s inner city to embrace pro-violent values and attitudes. Subcultural theories do not adequately explain racial disparities in crime. All these theories have a focus on African-Americans in impoverish areas. The subcultural theories offered also have a concentration on street crime. No theory seems to offer reason as to why the elite commit white-collar crimes. Furthermore these various subcultures that focus on pro-violent cultures do not give insight on how the pro-violent cultures came to be in the first place.
Fe-AZT and Pd-AZT Synthesis and Effects
Fe-AZT and Pd-AZT Synthesis and Effects Synthesis and Effects of Fe-AZT and Pd-AZT on Viability of Human Hepatocytes and Hepatocellular Carcinoma Cells Submitted by: Anna Harutyunyan Introduction Cancer is one of the major causes of mortality in the world. In 2015, according to the National Cancer Institute, over 1.6 million new cases of cancer were reported in the United States. The estimated cancer deaths for the year of 2015 were over 500,000. According to the National Cancer Institute projections, in 2016 an estimated 1.7 million new cases of cancer were diagnosed in the United States and 595,690 people will die from the disease (National Cancer Institute). Although new cancer treatments and therapies are designed and implemented every year, cancer is still the number two cause of mortality in the United States, therefore developing and testing new effective anticancer agents is crucial. Hepatocellular carcinoma (HCC) is one of the deadliest forms of cancers (Venook et al., 2010). The overall 5-year survival rate of HCC is less than 17%, making HCC the fastest rising cause of cancer related death in the United States (American Cancer Society 2016; Mittal and El-Serag, 2013). The annual age-adjusted incidence rates of HCC increased from 1.4 per 100,000 individuals in 1975-77 to 4.8 per 100,000 in 2005-07. An estimated 39,230 new cases of liver cancer (including intrahepatic bile duct cancers) were expected to occur in the US during 2016, approximately three-fourths of which would be hepatocellular carcinoma. An estimated 27,170 liver cancer deaths were expected in 2016 (American Cancer Society 2016). In 80-90% cases HHC occurs with and after cirrhosis. HCCs major risk factors are Hepatitis B and C viruses, cirrhosis, non-alcoholic fatty liver disease (NAFLD), overconsumption of alcohol and exposure to other carcinogenic substances (Mittal and El-Serag, 2013). Liver ca ncer is the sixth most common neoplasm and the third leading cause of cancer-related deaths, accounting for approximately 600,000 deaths annually (Venook et al., 2010). Because of early metastasis and progression, HCCs treatment is difficult, and traditional chemotherapy has shown limited success (Sabokrough et al, 2014). A research study published in 2015 suggested that an organometallic complex of platinum (II) azidothymidine (Pt (II)-AZT) has an antitumor effect on rat hepatocellular carcinoma cells. It was shown that this complex was significantly more effective in tumor suppression than the AZT without platinum (Sabokrough et al., 2014). Several organometallic complexes of AZT (with Zinc, Cobalt, Copper and Iron) were synthesized and characterized previously. The Iron complex of AZT (Fe-AZT) was shown to be the most stable (Shirvastav et al.) and have antimicrobial activity against 4 groups of bacteria. Electron rich ligands like AZT effectively bind and interact with metal ions producing metallodrugs which offer promising therapeutic application in terms of combating the drug-resistant strains of pathogens. It is also logical that a metal ion can influence the biological activity and therapeutic efficacy of the bio-molecule they bind (Shirvastav et al.) Thus it is useful to investigate the effect of a metal ion on the efficacy and mode of action of AZT in suppressing malignant cells and inducing apoptosis. To date, no research has been published regarding synthesis of Pd-AZT the inhibitory effect of both Fe-AZT and Pd-AZT on malignant cells. The aim of this research project is to synthesize Fe-AZT and Pd-AZT, confirm their structure and molecular mass and test their effects on viability of human hepatocellular carcinoma cells and normal human hepatocytes. Background Normal cell cycle In order to understand the biology of cancer it is crucial to understand the cell cycle of normal cells and cancerous cells. All cells in a given organism are under strict control of multiple regulatory agents, such as RB or p53 that control cell growth and keep the proliferative index stable. If there is a need for the cell to divide, the proliferative genes will turn on, or the suppressor genes that keep proliferation from occurring will be shut down, which will result in cell division (Hardin et al., 2014). The normal cell cycle consists of the following phases: G1, S, G2, M. During the G1 phase duplication of organelles, membrane systems and other important components happens. There is an important checkpoint at the end of this phase referred to as the restriction checkpoint, which verifies that DNA synthesis was successful and no errors have been detected. Next is the S phase during which the cell duplicates each chromosome. During the G2 the rest of the components that were not synthesized in the G1 phase are synthesized. A checkpoint after this phase makes sure the cell is ready to divide, and no errors in chromosome duplication were made. Mitosis is the next phase, when the cell physically divides (cytokinesis) making two identical daughter cells. A checkpoint during this phase checks if both of the daughter cells received the correct number of chromosomes. After division, the cell may remain in its silent G0 phase, when it does not divide, but continues to function. If any errors are detected on any of the checkpoints, the cell cycle is put on hold and the cell will undergo apoptosis. This process is governed my many enzymes and complexes, and theoretically, malfunction of any of these enzymes may result in uncontrolled cell division/proliferation. This can be the onset of carcinogenesis. Figure 1. The cell cycle phases with their checkpoints. Cancer cell cycle It is important to note that the normal cell cycle is under control of thousands of regulatory elements that are coded for by different genes. If mutations occur in the genes that code for the key elements keeping cell proliferation at bay, one level of control over the cell cycle is lost. There are cell signaling mechanisms through which immune cells detect faulty cells, send them death signals and the faulty cell undergoes apoptosis. It takes more than one mutation for a normal cell to start behaving like a cancer cell. Usually it is either the loss of the function of suppressor genes, or overexpression of proliferative genes that result in uncontrolled cell proliferation. When the cell becomes malignant, it loses the ability to respond to death signals, thus does not undergo apoptosis. The malignant cell cycle is slower than the normal cell cycle, however, since the cancer cells keep dividing and do not die, their number grows exponentially resulting in tumors (Weinberg, 2014). There is distinct cytological difference between normal and cancer cells (Figure 2). A normal cell has a smaller, regularly shaped nucleus, a low nucleus/cytoplasm ratio, is well differentiated and has well defined borders. Cancer cells have larger, irregularly shaped nucleus, high nucleus/cy toplasm ratio, are less differentiated and have irregular borders. In contract with normal cells that adhere to each other, cancer cells are less adhesive and break away from each other (Weinberg, 2014). Figure 2. The comparison of the cytology of normal cells and cancer cells. Azidothymidine (AZT), Fe(III)AZT, Pd(II)AZT Azidothymidine (AZT, Zidovudine) is a thymidine derivative in which the 3-hydroxy group is replaced by an azido group (Figure 3). It has been shown to have antitumor effects on different animal carcinoma cells both in vitro and in vivo through inhibition of telomerase activity and by causing cell cycle arrest (Gomez et al., 2012; Hadizadeh et al., 2014, Cooper and Lovett, 2011; Matteucci et al., 2015). Figure 3. Thymidine (left), Azidothymidine (right). Since cancer cells have higher proliferation rate than normal cells, their thymidine turnover rate is higher, which could contribute to their increased sensitivity to AZT. Several studies conducted by Fang et al., have shown that a hepatocellular carcinoma cell line (HepG2) is significantly more sensitive to AZT toxicity as compared to the normal hepatocyte (THLE2) sensitivity (Fang et al., 2014; Fang and Beland, 2009). The current hypothesis on how AZT affects the cell suggests that AZT is phosphorylated intracellularly yielding AZT-triphosphate and AZT-monophosphate. The AZT-monophosphate can be incorporated into the DNA structure instead of thymidine due to its similar molecular structure and shape. However, in contrast with thymidine, AZT lacks the 3 hydroxyl group which is the group that forms phosphodiester bonds between nucleotides in the DNA backbone structure. This means, wherever the AZT phosphate is incorporated in one of the DNA strands during DNA replication, the elongat ion of that strand halts (Figure 4). This is one of the mechanisms through which AZT causes damage to DNA (Fang et al, 2014). The commercial name of AZT is Zidovudine, and it is the basis of AIDS treatments. AZT blocks the replication of HIV-1 virus by competitively inhibiting the viral reverse transcriptase (RT). In other words, HIV RT prefers AZT to normal nucleotides. As described above, AZT is phosphorylated to AZT-triphosphate and is incorporated into viral DNA, halting nucleotide chain elongation. It is also known that AZT-triphosphate can be incorporated into eukaryotic DNA, although its affinity for DNA polymerases is lower than that for RT (Gomez et al, 2012). It was shown that Pt(II)-AZT is more effective in suppressing cancer cells than AZT, thus it has been suggested that having a transition metal bound to the central nitrogen atom of the azido group increases the complexs affinity for G-C and A-T base pairs and the P-backbone of DNA (Das and Pitre, 2007; Sabokrouh et al, 2015). Materials and Methods Fe-AZT and Pd-AZT synthesis To carry out the synthesis of Pd and Fe complexes, solid AZT and a standard ion solution of each metal (iron nitrate nonahydrate (Fe(NO3)3Ãâà ·9H2O and palladium chloride (PdCl2)) will be purchased from Sigma Aldrich (St. Louis, MO). Synthesis will be performed according to the protocol by Das and Pitre (2007). A 1:1 molar ratio of aqueous solution of AZT and metal ion will be refluxed for 3 hours. The volume of the reaction mixture will be reduced by 75% in order for the complex to precipitate. The solid product will be vacuum filtered, washed twice with ice-cold water, recrystallized and air-dried overnight. Infrared absorbance spectra will recorded for the AZT, Fe-AZT and Pd-AZT complexes. In the experiment conducted by Das and Pitre (2007) the comparison of IR spectra of pure AZT and its complex with Fe, the spectrum indicated a shift in bands from 2170 to 2150 cm-1 due to complexation through N atom of azido group. A similar band shift in the IR spectrum of Fe-AZT and Pd-AZT is expected. A Matrix Assisted Laser Ioniation/Distortion Time-of-Flight (MALDI TOF) mass spectrometry analysis will be performed for the Fe-AZT and Pd-AZT to determine the molar mass and the stoichiometry of the complexes. The matrix for analysis will be composed of 1:1 saturated Anthranilic Acid and Nicotinic Acid (Sigma Aldrich, St. Louis, MO). The samples and matrix will be dissolved in 45% acetonitrile: 55% water (van Kampen et al., 2004). Cell cultures HepG2, THLE2. Liver carcinoma cell line HepG2 and normal human liver cell line THLE2 will be obtained from American Type Culture Collection (Manassas, VA). The standard protocol recommended by ATCC will be used for establishing and maintaining hepatic cell lines. The cell lines will be plated at a density of 5 x 103 cells/cm2. HepG2 cells will be cultured in DMEM with 10% fetal bovine serum and antibiotics (penn/strep). THLE2 cells will be cultured in LHC-8 medium with 70ng/ml phosphoethanolamine, 5ng/ml epidermal growth factor, 10% fetal bovine serum and antibiotics (Fang et al., 2009). After ensuring sufficient cell growth and several passages of each cell line, the two cell lines will be divided into 4 groups each: control (no treatment) and treated with each drug: AZT, Fe-AZT and Pd-AZT (Table 1). Table 1. The experimental setup of the control and experimental groups of cells. Control 1 (C1) THLE2 cell line (no treatment) Control 2 (C2) HepG2 cell line (no treatment) Experimental 1 (E1) THLE2 cell line+AZT Experimental 2 (E2) HepG2 cell line+AZT Experimental 3 (E3) THLE2 cell line+Fe-AZT Experimental 4 (E4) HepG2 cell line+Fe-AZT Experimental 5 (E5) THLE2 cell line+Pd-AZT Experimental 6 (E6) HepG2 cell line+Pd-AZT The cells in the treated groups will be further categorized by the concentrations of the drug. HepG2 cells will be incubated with 2, 20 or 100 Ãâà µM aqueous solution of AZT, Fe-AZT or Pd-AZT for 14 days. THLE2 cells will be incubated with 50, 500 or 2500 Ãâà µM aqueous solution of AZT, Fe-AZT or Pd-AZT for 14 days. Each group of cells will be seeded at 5 x 103 cells/cm2 density in 6-well plates. The cells will be passaged weekly during the two-week treatment period. The dosage and incubation time were chosen based on a similar study (Fang et al., 2013; Matteucci et al., 2015; Sabokrouh et al., 2015). Cell viability assay After 14-day treatment period, 103 106 cells from each group will be seeded in a 96-well plate, incubated for 4 hours, and treated with MTT reagent, followed by a 8-12 hours incubation at 37Ãâà °C. After the incubation with MTT, when the cells have metabolized the yellow tetrazolium dye (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide) to purple formazan, the cells will be treated by a detergent to release the formazan into the solution, and the absorbance will be measured at 570nm using an ELIZA reader. The number of metabolically active cells will be determined using a previously made calibration curve. The statistical differences will be calculated using a Two-Way ANOVA and Tukeys Post-Hoc Test. Anticipated outcomes. The expected mass-to-charge ratio from mass spectrometry analysis of Fe-AZT complex is 323.1, that of Pd-AZT is 373.6. Based on the published literature and the adopted hypothesis, all three drugs are expected to decrease cell viability. The concentration of either drug should have positive correlation with decrease in cell viability. Based on previous observations, it is expected that the HepG2 cells will be significantly more sensitive to both complexes, thus will be significantly less viable after the treatment compared to the THLE-2 cells. Study Participants and Timeline Anna Harutyunyan is the primary author of this study. She is currently a senior biology and chemistry major at Wilson College. This project will serve as Annas senior research project. She will conduct the research and present the results with the supervision of her advisors Dr. Deborah S. Austin (Sponsoring PAS member) and Dr. M. Dana Harriger (PAS Member). The research study began in September 2016 and will be completed by April 2017. Annas research findings will be analyzed and written as her senior thesis. Anna will also present her findings at the 2017 Pennsylvania Academy of Science meeting and at the Wilson College research colloquium. Budget Item Price MTT Assay Kit (ThermoFisher) $235.00 Zidovudine (Sigma) $124.00 LHC-8 medium (Gibco) $140.00 Total $499.00 Facilities and Equipment The MALDI TOF mass spectrophotometer will be provided by Pennsylvania State College of Medicine Mass Spectrometry Facility under supervision of Bruce Stanley, PhD. All materials, other instruments, and equipment not listed, including cell culture media and supplies, will be provided by the Department of Physical and Life Science of Wilson College. References à à American Cancer Society. Cancer Facts Figures 2016. Atlanta: American Cancer Society; 2016. Bilsland AE, Stevenson K, Liu Y, Hoare S, Cairney CJ, Roffey J, et al. (2014) Mathematical Model of a Telomerase Transcriptional Regulatory Network Developed by Cell-Based Screening: Analysis of Inhibitor Effects and Telomerase Expression Mechanisms. PLoS Comput Biol 10(2): e1003448. doi:10.1371/journal.pcbi.1003448 BIOL2060 Cell Cycle [Photograph found in Department of Biology Memorial University of Newfoundland]. (2015). In Hardin Bertoni (Authors). Retrieved March 30, 2016, from http://www.mun.ca/biology/desmid/brian/BIOL2060/BIOL2060-19/CB19.html Chen, Yi-Bin. Liver Cancer Hepatocellular Carcinoma: MedlinePlus Medical Encyclopedia. U.S National Library of Medicine. U.S. National Library of Medicine, 1 Aug. 2015. Web. 10 Apr. 2016. Cooper, D. L., Lovett, S. T. (2011). Toxicity and tolerance mechanisms for azidothymidine, a replication gap-promoting agent, in Escherichia coli. DNA Repair, 10(3), 260-270. http://doi.org/10.1016/j.dnarep.2010.11.007 Das, R., Pitre, K. S. (september 2007). Bioinorganic studies on Fe (II)- zidovudine (azt) complex. Indian Journal of Chemical Technology, 14, 526-528. Retrieved February 20, 2016. Fang, J.-L., Beland, F. A. (2009). Long-Term Exposure to Zidovudine Delays Cell Cycle Progression, Induces Apoptosis, and Decreases Telomerase Activity in Human Hepatocytes. Toxicological Sciences, 111(1), 120-130. http://doi.org/10.1093/toxsci/kfp136 Fang, J., Han, T., Wu, Q., Beland, F., Chang, C., Guo, L., Fuscoe, J. (2014). Differential gene expression in human hepatocyte cell lines exposed to the antiretroviral agent zidovudine. Archives Of Toxicology, 88(3), 609-623. doi:10.1007/s00204-013-1169-3 Gomez, D. E., Armando, R. G., Alonso, D. F. (2012). AZT as a telomerase inhibitor. Frontiers in Oncology, 2, 113th ser. Retrieved March 11, 2016, from http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3434370/ Hadizadeh, S., Najafzadeh, N., Mazani, M., Amani, M., Mansouri-Torshizi, H., Niapour, A. (2014). Cytotoxic Effects of Newly Synthesized Palladium(II) Complexes of Diethyldithiocarbamate on Gastrointestinal Cancer Cell Lines. Biochemistry Research International, 1-9.doi:10.1155/2014/813457 Hardin, J., Bertoni, G., Kleinsmith, L. J., Becker, W. M. (2014). Beckers world of the cell (8th ed.). Boston: Benjamin Cummings. Harrington, J. A., Reardon, J. E., Spector, T. (1993). 3-azido-3-deoxythymidine (AZT) monophosphate: an inhibitor of exonucleolytic repair of AZT-terminated DNA. Antimicrobial Agents and Chemotherapy, 37(4), 918-920. van Kampen Jeroen J.A., Fraaij Pieter L.A., Vishal Hira, van Rossum Annemarie M.C., Hartwig, Nico G., de Groot Ronald, Luider Theo M.. A new method for analysis of AZT- triphosphate and nucleotide-triphosphates. Biochemical and Biophysical Research Communications, Volume 316, Issue 3, 9 April 2004, 151-159] Matteucci, C., Minutolo, A., Marino-Merlo, F., Grelli, S., Frezza, C., Mastino, A., Macchi, B. (2015). Characterization of the enhanced apoptotic response to azidothymidine by pharmacological inhibition of NF-kB. Life Sciences, 127, 90-97. doi:10.1016/j.lfs.2015.01.038 Mittal, S., El-Serag, H. B. (2013). Epidemiology of HCC: Consider the Population. Journal ofClinical Gastroenterology, 47(0), S2-S6.http://doi.org/10.1097/MCG.0b013e3182872f29 National Cancer Institute. (n.d.). Surveillance, Epidemiology, and End Results Program. Retrieved February 16, 2016, from http://seer.cancer.gov/statfacts/html/all.html Neto, V. (2013, January). AZT action [Photograph found in Organic Chemistry]. Retrieved April 1, 2016, from http://wwwblogvine.blogspot.com/2013/01/azt-was-originally-intendedto- treat.html (Originally photographed 2013, January 20) Normal And Cancer Cells Structure [Photograph found in Cells or Tissue Abnormal Cells or Tissue Cells or Tissue Normal Cells or Tissue Historical Graphics, National Cancer Institute]. (2001, January 1). In P. Kenny (Illustrator). Retrieved April 1, 2016, from https://visualsonline.cancer.gov/details.cfm?imageid=2512 (Originally illustrated 1990, April) Pichard, L., Raulet, E., Fabre, G., Ferrini, J. B., Ourlin, J. C., Maurel, P. (2006, February). Human hepatocyte culture. Retrieved March 11, 2016, from https://www.researchgate.net/publication/7063976_Human_hepatocyte_culture Sabokrouh, A., Vaisi-Raygani, A., Goodarzi, M. T., Khatami, S., Taghizadeh-jahed, M., Shahabadi, N., à ¢Ã¢â ¬Ã ¦ Shakiba, Y. (2015). Comparison between Platinum-Azidothymidine and Azidothymidine Effects on Bcl-2 and Telomerase Gene Expression in Rats with Hepatocellular Carcinoma. Avicenna Journal of Medical Biotechnology, 7(2), 50-56. Sabokrouh, A., Goodarzi, M. T., Vaisi-Raygani, A., Khatami, S., Taghizadeh-Jahed, M. (2014). Effects of Treatment with Platinum Azidothymidine and Azidothymidine on Telomerase Activity and Bcl-2 Concentration in Hepatocellular Carcinoma-Induced Rats. Avicenna Journal Of Medical Biotechnology, 6(4), 200-209. Telomere Shortening Determines the Proliferative Lifespan of Human Diploid Fibroblasts. 2001. Nature Reviews. By Nicole F. Mathon and Alison C. Lloyd. Web. 21 Mar. 2016. ThermoFisher Scientific. (n.d.). MRNA Extraction. Retrieved March 11, 2016, from https://www.thermofisher.com/us/en/home/life-science/dna-rna-purification-analysis/rna- extraction/rna-types/mrna-extraction.html Venook, A. P., Papandreou, C., Furuse, J., De Guevara, L. L. (2010). The Incidence and Epidemiology of Hepatocellular Carcinoma: A Global and Regional Persprective. The Oncologist, 4(15), 5-13. Retrieved March 11, 2016, from http://theoncologist.alphamedpress.org/content/15/suppl_4/5.long Weinberg, Robert A. The Biology of Cancer. 2nd ed. New York, NY: Garland Science, 2014. Print.
Tuesday, August 20, 2019
The Struggles Faced In The Color Purple And The Joy Luck Club Essay
The Struggles Faced in The Color Purple and The Joy Luck Club A common bond of struggle links the novels The Color Purple by Alice Walker and The Joy Luck Club by Amy Tan. Rape, suicide, death, war, oppression, and racism invade the two novels. In The Color Purple, Celie overcomes racism, violence, and other issues to find dignity and love. In the Joy Luck Club, the daughters struggle for acceptance, love, and happiness. Though the characters endure many hardships they survive not only by not becoming bitter individuals but becoming more whole individuals. Celie in The Color Purple has struggled since the very beginning because of the poor treatment she has received by men. Being raped by her father Fonso, Celie becomes pregnant and Fonso sells both of the children that she has. Celie promises to protect Nettie, her sister, from Fonso's abuse is the first sign of her taking a stance to prevent the horrors which are occurring in her patriarchal existence. When married her husband Albert just uses her as a slave. He perceives her as livestock, and denies her not only love but humanity (Hall, 3) The first night together he raped her. She worked on the farm and put up with his children. At 14 she writes notes to God on the dehumanizing nature of her existence and the humiliations she has suffered (Kirkpatrick, 846). Although she totally devalues herself, Celie finds her sister very valuable, worth protecting. Her selflessness and lack of bitterness are evident here. Celie shows resentment and bitterness at the way she has been treated by men. Albert also betrays her by hiding all of the letters from Nettie making Celie believe that her sister is dead. She also feels betrayed by God, who seems to her to have condoned much of the strife in her life. Celieââ¬â¢s life has been one of hopelessness, even longing for death as a relief from lifeââ¬â¢s hardships (Hankinson, 3) Shug suggests to her that the ultimate goal for people is life giving rather than life denying. Celie is also a prime example of trying to overcome her struggle to find who or what she wants to be. Shug Avery is a symbol to Celie of the ideal women that she wants to be. Shug is also a symbol of life, freedom, and love. Celie is submissive and abused often. However, she has not lost her intelligence and keeps her anger in check and doesnââ¬â¢t do anything rash for the sake of seeing her sister again. In ... ...à à à By examining the characters of The Color Purple and The Joy Luck Club, one can conclude that many of the characters face struggles throughout the two novels. Each character finds their own way to deal with their struggles. Celie finds a new self-respect and strength while the daughters in The Joy Luck Club realize the strength and dignity of her mother and learn to appreciate her Chinese heritage. Works Cited Hall, James C. ââ¬Å"Towards a Map of Mis(sed) Reading: The Presence of Absence in the Color Purpleâ⬠African American Review (Spring 1992):2-6 Hamiliton, Patricia L. ââ¬Å"Feng Shui, Astrology, and the Five Elements: Traditional Chinese Belief in Amy Tanââ¬â¢s the Joy Luck Clubâ⬠MELUS (Summer 1999):1 Hankinson, Stacie L. ââ¬Å"From Monotheism to Pantheism: Liberation from Patriarchy in Alice Walkerââ¬â¢s the Color Purpleâ⬠Midwest Quarterly (Spring 1997): 3 Heung, Marina ââ¬Å"Daughter-Text/Mother-Text: Matrilineage in Amy Tanââ¬â¢s Joy Luck Clubâ⬠Feminist Studies (Fall 1993): 3 Kirkpatrick, D.L. ââ¬Å"Alice Walkerâ⬠1986. New York, NY: St. Martinââ¬â¢s Press. 846 Schell , Orville ââ¬Å"Amy Tan the Joy Luck Clubâ⬠March 1989. New York: 1989. 92 Tan, Amy. The Joy Luck Club. 1989. New York: G.P. Putnam
Monday, August 19, 2019
Islamic Economy in Saudi Arabian Companies Essay -- Economics
1. Saudi Companies Fund A. The institution of SAMA could not be a profit-making institution, it had to conform to Islamic law. SAMA has from time to time financed one-half of government debt. From 1962 to 1983, the governments earning grew in surplus, and all the debt was repaid. Whenever the government needed SAMA bolstered government reserves. B. In 1966 a major banking control law clarified and strengthened SAMA's role in regulating the banking system. Foreign banks submitted application for license. SAMA sent its recommendation to the ministry of finance. The ministry set conditions for granting licenses to foreign banks. C. Saudi companies introduced a great deal of regulation abiding with Sharia law. This law also defined requirements against deposits. There were several restriction to abide by SAMA's implementation of monetary policy. 2. The Saudi financial system A. The Saudi financial system had three autonomous government institutions. They were the pension fund, the general organization of Saudi insurance, and Saudi fund for development. These government instit...
Sunday, August 18, 2019
Introduction to Fiction Final Paper :: English Literature Essays
Introduction to Fiction Final Paper Introduction: I will try to show that Fenstad's mother is going through a change during this story. At first she is described as a strong independent woman very active social in control of things. She is not accepting things as they are she tries to change the things that seem wrong to her. However, gradually we are starting to see her as an old woman who hates her age. A woman, who has a hard time excepting her age and all the downsides of it, a woman whose physical condition is parallel to her mental and emotional state, who needs help doing things which young people do without any effort. It seems that during the story Fenstad and his mother change places. Once he was dependent on her and now gradually we see that she is more and more dependent of her son. Fenstad's mother is gradually going through the process of accepting her age and the changes she is going trough consequently. It is difficult for her at first however eventually she stops being preoccupied with the past and what she once was. She comes to terms with her life and learns to appreciate and enjoy the little (simple) pleasures of life, like music. The name of this fiction story is Fenstad's Mother, the word mother is written with a capital letter which sometimes can mean a woman in charge of some community. This description is suitable for her character as it is described at the beginning of the story. Clara Fenstad's going to her son's class, meeting the people that took this class, listening to them and being loved and appreciated by them helps her through this period. One of this people influenced her very much and was responsible for one of the various changes she went through. The fact that Fenstad's mother learned to accept him as he made them closer and happier. Fenstad's Mother: At the beginning of the story Fenstad's mother is shown like a strong and active woman. She is very much involved in the things that happen around her. She is progressive and social. "Fenstad's mother was a life long social progressive" (p.115). She is not taking seriously her sons churchgoing, "was amused by her son's churchgoing. She had spent her life in the company of rebels and deviationists, and she recognized all their styles." (p.115). She is very logical and attentive, "She glanced down at his trousers, damped with melted snow. "You've been skating" "(p.116) she is aware of her son's habits, but not necessary approves of them. She sneers her son's behavior and looking for slips in it.
Saturday, August 17, 2019
Tarantella Poetry Commentary
The poem Tarantella is structured into two stanzas. The stanzas are unequal in length as the first stanza is longer than the second. The poem also consists of a chorus which is repeated 3 times. The chorus in the poem is ââ¬Å"Do you remember an Inn? Miranda? Do you remember an Inn? â⬠. Tarantella is about the memories of a specific Inn; ââ¬Å"Do you remember an Inn, Miranda? â⬠. The poem is set during war which is shown by the imagery used. The poem describes the bad experience of staying at an inn during war because of the ââ¬Å"straw for a beddingâ⬠and the ââ¬Å"wine that tasted of tarâ⬠. The tone of the poem is energetic which is created by the quick speed of the rhythm. The irregular lines of the poem are long or short which helps to create the quick speed. . The short lines also contribute towards the speed. In the poem, ââ¬Å"And the cheers and the jeers of the young muleteersâ⬠is repeated as part of the technique used. Other techniques used in the poem include couplets and onomatopoeia. The poem has a fast rhythm. The effect this creates is an upbeat and energetic tone. The rhythm is created by the flow of the poem and the rhyming of the different lengths of lines. Tarantella can also be danced to as it is also a lively folk dance in 6/8 time. There are theories about the dance and one of those is that the dance is a cure for spider bites. Another theory is that when one is bitten by a spider, the victim would have the urge to dance uncontrollably. The poem rhymes irregularly in couplets or sometimes in the lines. An example of the poem rhyming in lines is ââ¬Å"the fleas that tease in the High Pyrenees. As Tarantella is a dance, the music of the dance also goes along with the poem. Tarantella has two metaphors which help set the imagery. The last stanza shows that the poem is set during war. This is shown by the two metaphors that are in the last stanza. The metaphor ââ¬Å"Aragon a torrent at the doorâ⬠shows that Aragon is ââ¬Å"at the doorâ⬠and ready for war. The other metaphor ââ¬Å"Waterfall like Doomâ⬠is about the bombs th at are falling, and flowing like a waterfall creating a ââ¬Å"boomâ⬠. In the poem ââ¬Å"the feet of the dead to the groundâ⬠describes the victims of the war. The victimââ¬â¢s feet are on the ground meaning that they have fallen and died. The poem is alerting people that are going to experience war, about how it feels. This is shown by some of the negativity about the experience, as well as some of the good memories of it. Some examples include, ââ¬Å"Straw for a beddingâ⬠, ââ¬Å"wine that tasted of tarâ⬠ââ¬Å"cheers and jeersâ⬠. The person that would be alerting people would have experienced war themselves.
Friday, August 16, 2019
Pencils Are Better Than Pens – Debate
Pencils are better than Pens Ladies and gentlemen, When you go to war you want to be prepared with the right weapons. Having the wrong ones can limit you success and impair your skills. Isnââ¬â¢t this the same case for writing a paper? When you sit down to write a paper you want to make your ideas flow, to be able to erase false ones, and stay focused; pencils enable you to do all of those things more effectively than pens. Pencils have erasers to fix all your mistakes, theyââ¬â¢re 100% organic, and contrary to pens, which can be very messy, pencils are neat and long lasting.When you are writing, you make mistakes all the time. You write words messily, you spell them wrong, and you mix up the order of what you are trying to say. If you are writing with a pen you have to scribble out all of those misspelled words or draw arrows to where you want things to be. When youââ¬â¢re done, it looks like a paper in disarray. If you write with a pencil you donââ¬â¢t have to do any of that. You can erase all of your misspelled words, and neatly move sentences to where ever you want. When youââ¬â¢re finished your paper looks faultless.It has no messy scribbles or long confusing arrows, everything is precisely how you want it to be. Of course scientists have created an erasable pen, but it doesnââ¬â¢t work as well as pencils. Erasable pens can erase, but they normally leave streaks or smudges on the page. You also canââ¬â¢t just use any eraser on it, it has to be a special eraser that costs more than a regular pencil eraser. Pencils are much more affective at erasing and keeping papers mess free. Secondly, pencils are 100 percent organic. They are made up of cedar, graphite, and metal.Which are all organic substances. Pens are made up of plastic and ink. Ink is made up of oil, which is harmful to the earth. Plastic is not organic, and pollutes the environment. Also if you break a pen in half, it is permanently broken, and becomes incredibly messy. Once th ey are broken they end up getting thrown away, and produce more trash. When a pencil is broken in half. All you have to do is sharpen it, and you have two pencils! This then reduces the amount of wasted materials. With that in mind, pens are much messier than pencils. Pencils canââ¬â¢t write n you or other objects besides paper. But pens on the other hand can write on almost any surface. Even when you write, you can smudge it all over your page when its not dry, it gets all over your hands, and itââ¬â¢s very hard to get off of your skin. Once your skin absorbs the ink it can give you ink poisoning. But pencils canââ¬â¢t poison you, or do anything permanently harmful to you, and they are mess free. Lastly, pencils are a very useful and long lasting utensil. According to Dixon Ticonderoga Pencil Company, pencils can draw a line 35 miles long.And according to bicworld. com pens can draw a line 1. 24 miles long. Using one pencil is the equivalent to using 28 pens. One organic p encil eliminates much more waste than 28 pens do. In conclusion, pencils are the prime utensil for writing a paper. Pencils have erasers to erase all your mistakes. They are 100 percent organic, and unlike pens they are neat and long lasting. You don't want to impair your skills nor limit your success, so when you sit down to write a paper, remember to use the better writing utensil, the pencil. Thank you.
Thursday, August 15, 2019
Moral Dilemas: Antigone Essay
One of the most difficult trials I face in my life are ethical and moral dilemmas. I believe one purpose for this life is to learn to act for ourselves and learn to see a situation correctly and act righteously. Everyday Iââ¬â¢m faced with decisions of right and wrong, most of which are easily and correctly dealt with. Sometimes however, decisions need to be made that are not easy or perfectly clear. In this paper I wish to discuss a presented moral dilemma and explain what I would do in the same situation. One of the biggest conflicts in the play ââ¬Å"Antigoneâ⬠by Sophocles is the value of human law vs. divine law. In this tragic play a newly appointed king Creon declares to his people that treason was committed during battle, and one of the two brothers (Polyneices) killed shall not be buried. This dilemma is felt by many, especially Antigone (sister of Polyneices). The struggle between human law and divine law is a moral dilemma Antigone feels as she decides to go against the laws of the king. The moral dilemma being presented is from the perspective of a pharmacist. The pharmacist has a young sick niece who has a terrible ear infection and cannot get an appointment with the doctor until the next day. The pharmacist knows that she doesnââ¬â¢t have a prescription, but knows what type of antibiotic she probably needs. Does the pharmacist give the medicine to the niece? If I were in the position of the pharmacist, I would refuse to give the medicine to my niece. I wouldnââ¬â¢t give the medicine to my niece because of the consequences that I would be dealt if I were too. My position on the dilemma is similar to Ismineââ¬â¢s (Antigoneââ¬â¢s sister) when trying to convince Antigone not to bury her brother. If the pharmacist helps then he/she will get fired, go to jail, and probably never work as a pharmacist again. This turns a short term problem into a long term problem which will influence the rest of your life. Is an ear infection worth going to jail and possibly ruining your life?
China One Child Policy Essay
Imagine a world where one canââ¬â¢t just simply go to the supermarket because there is not enough food. A world where pollution is a daily reality, the air too thick to even breath and the water virtually undrinkable. A place you can no longer buy consumer goods because there isnââ¬â¢t enough materials to make them. This could become a reality, but preventing it has always been on the minds of the Chinese government. War and epidemics had struck China for years, but after the founding of the Peopleââ¬â¢s Republic of China, sanitation and medicine improved and prompted rapid population growth. This combined with the movement created by Mao Zedong, Chinaââ¬â¢s previous communist leader, led to rapid population growth that gave Chinaââ¬â¢s monumental population. This monumental mistake took its toll in the food supply when Mao emphasized steel production over farming, food supply slipped behind population growth; by 1962 a massive famine had caused some 30 million deaths. After the population leveled off, the government continued the camping to reduce Chinaââ¬â¢s population. In 1979 the Chinese government introduced a policy requiring couples from Chinaââ¬â¢s ethnic Han majority to have only one child. Depending on where they lived parents can be fined thousand of dollars for having an extra child without a permit and can be forced to abort the child and then be sterilized. With all this in mind I not only believe that the one child policy with some adjustments can be a good solution to the overpopulation and issues related to it but also it is a necessary policy. With changes to the policy will greatly improve Chinaââ¬â¢s people living environment and standards. Without this policy we can face serious issues concerning food supplies, depletion of natural resources at a rapid rate, poverty,spreading of diseases due to lack of proper medical care, overcrowded cities that can lead to heavy pollution, inadequate housing, lower life expectancy and higher death rates, educational facilities may not meet the population requirements,and finally lower employment opportunities that lead to unequal distribution of wealth. All of this could become a reality without the proper population control provided by the policy. Society a highly structured system of human organization for large-scale community living that normally furnishes protection, continuity, security, and a national identity. Some essential things that are required for the flourishment of a society are essentials such as food and water. This are non debatable requirements for cities to rise, survive and thrive. Over population can bring many obstacles and difficulties that could impede us from thriving as a society. Some include heavy pollution that is caused by factories that are needed to meet the demands of the big population. This pollution can be precipitated into the water sources can lead to the spread of diseases such as cholera and typhoids. Although higher population number will produce more food the earth can only support so much. Even with genetically modified (GMCââ¬â¢s) the land can only be used so much before it runs put of nutrients and then become useless. The overuse of the land will lead to soil erosion from trying to meet the food demands of a huge population. Air pollution can cause the spread of diseases such as asthma, COPD, cystic fibrosis, heart disease and even diabetes. This will lead to millions of death and could potentially wipe out entire populations and cause poor living conditions. The lack of proper medical care will be one of many factors also contributing to the decline of living standards and lower living expectancies which means higher death rates. Thomas Malthus wrote theories that predicted living conditions over many centuries. He stated that over population will cause more disadvantages that will outweigh the advantages. Some might said that in his theory he didnââ¬â¢t take into account the advances in technology that is essential to the prosperity of a country. I donââ¬â¢t argue that Malthus may not have taken that into account but it still doesnââ¬â¢t change the fact that earth has a finite carrying capacity. No matter how technology progresses or gets better it will be limited by the resources that we can get. Resources are limited. Technology could provide ways of using this resources more efficiently but no matter what we do it will always lead to the depletion because of higher demand caused by overpopulation. Although technology can solve many of our problems it has a great limitation. That limitation is us. The overcrowding of cities may lead to educational facilities not being able to provide the proper learning environment and fail to teach the population. This will cause high levels kids falling behind and not be able to contribute and move on to high level jobs in science, math or engineering which will slow down the rate of progression in technology, and without it we wonââ¬â¢t be able to meet the demands of a large population. Over population can cause lower employment opportunities that will leave many families in poverty. This will cause and uneven distribution of wealth that can cause the crime rate to go higher. Less jobs means the economy would be very limited or there will be a lot of jobs but minimum wage jobs. Families would be forced to sends their children to work so they can help support the family instead of sending them to school. With a smaller population more high level jobs can be given and more money means better standard of living and high life expectancy levels. Wealth can provide many things such as medical care, adequate housing,etc. All of this can be avoided with population control policies such as the one child policy. There is a lot of disadvantages that can cause a disastrous future. So we need to ask ourselves if that will be a life wen want to live in. The answer will always come down to no. The one child policy has harsh effects that are controversial. The forced sterilization and abortion of women is one of the horrid realities that the policy makes possible. But this doesnââ¬â¢t change the fact that the policy is a necessity. I completely agree that this must be change. New regulations can be put into place that are more passive and more widely accepted by the majority. The one child policy is a necessity that helps our society in many ways. The advantages of having this policy far outweigh the disadvantages. It keeps Chinaââ¬â¢s prosperity and encourages great economic wealth and progression. So I urge you to consider all of the points made and see that the one child policy is not only a smart choice but also a great one.
Wednesday, August 14, 2019
Canceling Third World Debt
There are many compelling arguments for canceling third world debt. However, regardless of how morally wrong, third world debt relief will not go very far in solving the myriad of causes underlying the poverty crippling these countries in the first place. Canceling the debt is just one step in the process. Industrialized countries must also be willing to reform world trade laws, drop subsidies that insulate the world markets, fight graft, and help poor countries eliminate the corruption that permeates their systems. Plagiarism Detection >Examples of this systemic corruption can be seen in the countries of Kenya, Zimbabwe, DRC, Nigeria or Tanzania. These so called indebted and poor countries are some of the richest in the world in natural resources who at the same time, have a well educated work force. Yet the people are poor because their government abuses them and their resources, keeping the wealth for a few rather than for all. Canceling the world debt will not trickle down to the people as long as corrupt government officials stand in the way.Canceling the debt may encourage more bad economic policy choices, while at the same time allowing irresponsible lender governments off the hook, free to form new alliances with criminal regimes. Much of this so called debt was merely a way for developed nations to carve out a stake in the natural resources of the poor country, in order to protect their personal interests. By canceling the debt corrupt lending countries can hide their complicity in the denigration of the poor country and its people. Hanging a blanket cancellation onto a country also means that it is not a creditworthy nation in the eyes of other world governments, making things worse. Plagiarism Detection >Nor does it stop the cycle of criminality, because the countries must still borrow in order to survive and meet their other debts in the future. One way third world countries can get out of the financial and poverty inducing rut is to stay away fro m the patronage of rich nations who put them in trouble in the first place. Another way is to demand respect and proper treatment from creditors while eliminating the corruption endemic in their governments. It has been proven over and over again that the criminality and graft is a two way street. International law already allows countries to repudiate debt contracted without the consent of, nor spent in the interests of the people.Under international law citizens of a country do not have to repay those financed their oppression such as America propping up tin hat dictators like Mbutu, to name one. What seems to be lacking is a will to eliminate the underlying root causes of third world problems. The tools for doing such are already there waiting to be used. Third world debt cancellation is merely addressing a symptom that will only give very short term relief while allowing the problem to recycle and become entrenched again. Breaking the cycle is the only way to alleviate the prob lem on a more permanent level.
Tuesday, August 13, 2019
Technology Make us Lazy and Dumb Essay Example | Topics and Well Written Essays - 750 words
Technology Make us Lazy and Dumb - Essay Example â⬠talks about the effects of various technological devices on the brain of young individuals. Stating that the average teenager in America has three to four electronic gadgets (ââ¬Å"Is Technology Messing with Your Brain?â⬠) the article states just how distracting these gadgets are. Giving everyday examples, the articles strives to show that these technological devices keep the minds of youngsters occupied so much that it does not have any time to rest, and consequently, there is the chance of losing its ability to concentrate. The article has also cited a study published in Pediatrics which showed that children who played a lot of video games before sleeping had lesser retention than those who had not (ââ¬Å"Is Technology Messing with Your Brain?â⬠). Overall, it explained the negative effects that technology and its use can have on our brains. The second article, ââ¬Å"The Digital Age is Making Us Physically and Mentally Lazy?â⬠discusses the same issue, but also talks about the physical effects or changes that technology has brought about in our lives. The article discusses the impact technology has on our physical activities by citing examples from everyday activities. It asserts that whereas before we had to be somewhat physically active to, for example, go meet a friend or go out for a movie, with technology, we do not have to make any physical excursion of the like, citing examples of texting friends and streaming movies on our computers (ââ¬Å"The Digital Age is Making Us Physically and Mentally Lazy?â⬠). However, the article does not agree with the contention that people are becoming mentally lazy due to technology. It, instead, asserts that due to technology making so much information available to us readily, people are actually becoming more knowledgeable than before (ââ¬Å"The Digital Age is Making Us Physically and Mentally Lazy?â⬠). Moreover, the article claims that even though technology has made live easier, bu t they have not removed the need to think in us, therefore, they have not made us mentally lazy (ââ¬Å"The Digital Age is Making Us Physically and Mentally Lazy?â⬠). In, ââ¬Å"Is Technology Messing with Your Brain?â⬠I found the examples of multitasking given to be very useful. Such scenes, where teenagers are involved in multiple activities are very familiar to us; therefore, it was easy to connect with her statement of how this multitasking makes a teenage brain less capable of concentrating on any given subject for long. Moreover, the results of the study that were put in the article were very helpful too. Through discussing the results of the study, the article has proffered proof of the assertions regarding technology lessening our brainââ¬â¢s retention powers. However, the article states that technology takes away from real-life relationships, and this I found to be quite contrary to reality. The logic herein is flawed, because though it may seem as if the kid w ho is hanging out with his computer all day is not hanging out with his friends or parents, in actuality, the teen does get to spend time with his parents and his friends online. Especially since, in an example the article itself gives, some of the kids require technology to be in contact with their parents as they do not live with them. In ââ¬Å"The Digital Age is Making Us Physically and Mentally Lazy?â⬠the way in which examples are given from everyday life is, indeed, very helpful. This makes the reader
Monday, August 12, 2019
Taiwanese and American Art Thesis Example | Topics and Well Written Essays - 11500 words
Taiwanese and American Art - Thesis Example Still, the Eastern art had a thoughtful impact on Western impressionists where the work was hailed as the ultimate performance art form by master dramatists (Hong 2005). A number of Western artists have expressed their fascination with the spirit of nature in Chinese paintings and how Chinese artists imprison it in a few strokes, thereby, making the blank space on a canvas as reminiscent as the painting itself (Hong 2005). The delineation of Chinese ink and wash landscapes held by this contemporary has caused a substantial blend within the capital's art circles. The last few decades have witnessed a blast in the ideas as well as the theories of art, for it has never been more popular, however, much present thinking remains out-of-the-way and difficult to use (Costello 2007). This thesis effectually delineates the Hybridity and association of the Eastern art with that of the West. The aim of this research is to investigate the similarities as well as differences between Western modernism and Taiwanese Ink and Wash painting, chiefly in their representations as well as the usage of pictorial space, time and color. ... This thesis effectually delineates the Hybridity and association of the Eastern art with that of the West. The aim of this research is to investigate the similarities as well as differences between Western modernism and Taiwanese Ink and Wash painting, chiefly in their representations as well as the usage of pictorial space, time and color. Abstract expressionism and surrealism play a significant role and the Traditional development of modern Ink and Wash painting during the period from 1949 to 2000. According to Bradley, Surrealism reflects the visual richness as well as vivacious confrontations in Documents between art, archaeology, ethnography and other popular culture (Bradley 1999). Moreover, it will focus upon some prominent Taiwanese modern Ink and Wash painters who were respectively influenced by the specific theories and figures of abstract expressionism as well as Surrealism. There have been examined several western methods and ideas which were adopted by the Taiwanese arti sts and their incorporation within the specific cultural contexts of the various schools of art that allow them to establish new, formal as well as stylistic innovations. These comparative perspectives will then be applied to Ink and wash modernists and the abstract expressionists with its leading representatives. 2. Introduction Ink and Wash painting is a genre of the conventional Chinese painting performed on Xuan paper in black with no other colors. Simple, yet elegant, it slowly and
Sunday, August 11, 2019
Sustainability in construction Essay Example | Topics and Well Written Essays - 1500 words
Sustainability in construction - Essay Example For example, the UK national Grid has planned to cut domestic emissions by 45% by 2029, while the European Union countries are in agreement to harness more than 20% of their energy from renewable sources by 2020; U.Kââ¬â¢s target is15% (Huang & Infield, 2002). In addition, Scotland and UK have plans to reduce carbon dioxide emissions by 80% by 2050, and a proposed reduction of about 42% by 2020 to curb the climate change threat (Tecs Home Energy Survey Report, 2010). Therefore, as the two articles indicate, energy usage in both domestic and in industrial applications has led to an environmental threat that has been caused by increasing global warming, as a result of carbon emissions from fossil fuels. Jones in the article Reducing emissions through energy efficiency correctly articulates that energy usage in buildings contribute to almost half of carbon emissions in U.K. This is in line with the figures indicated by Tecs Home Energy Survey Report (2010). As Jones illustrates, the UK government has come up with different measures in trying to reduce carbon emissions in line with 2010 proposed emission reductions. ... tial stages of industrialization results from the increasing greenhouse gas emissions in the atmosphere; this has resulted in the continued climate change, with temperatures in the U.K expected to increase by between 2 to 3.5 degrees centigrade this century. Therefore the intergovernmental panel set up to address this issue according to this report suggested building codes and designs that would eliminate any need for mechanical cooling in homes, which has been attributed to considerable portion of global warming gases in the atmosphere. The report suggests a new perspective in building and construction on how buildings might have special features, which might be responsive to climate changes, and which anticipate and are in accordance with future climate trends. Likewise, Jones in Reducing emissions through energy efficiency concurs with this argument and asserts that energy demand has to be maintained to a minimum by adopting more responsible designs, and adopting the use of renewa ble energy sources. This would include minimizing uncontrolled air infiltration through effective designs, and adopting natural ventilations. Generally according to Jones, this may be only achieved through an integrated design team to ensure harmonization, and good interactions between the various disciplines involved in building designs. This is an effective approach in reducing domestic energy usage, noting that more than 46 % of energy usage in U.K is through air conditioning, heating, cooling, and other general usage that may be controlled through proper designs (TECs Home Energy Survey Report, 2010). However, the article thermal comfort in a 21st century Climate puts much emphasizes on the need to control energy through responsible use of energy by tenants. The article suggests the use
Saturday, August 10, 2019
Current Events in Macroeconomics Essay Example | Topics and Well Written Essays - 750 words
Current Events in Macroeconomics - Essay Example They are especially critical of many levels of government intervention, including the proposed guest worker program. The two concur in many areas, including the fact that despite the illegality of this immigration, it benefits the economic status we enjoy by having the illegal immigrants take positions which are those others would not take in service industries like housekeeping and landscaping and other such jobs. The two also state that there are many pluses, including the fact that taxes are often paid by these illegal immigrants. The negatives, unfortunately, are also easily seen, including the use of public education, fire and police protection, and all forms of government assistance including Medicaid, Food Stamps and other such assistance. The overall concept for this article is encompassing human factors, how humanity affects the economy. In this particular case, how the migration and immigration of people affects a particular economy in both good and bad ways. This is subjec t to a great deal of debate as to whether or not such immigration would be of benefit and whether the attempts to change the idea would be of any economic merit. In the Economy section David Wessel writes in A Tricky Move for the Fed, Wall Street Journal June 24, 2006 issue, that the decision to change the interest rate up or down is a tricky proposition in current economic times. The reason for this is that finding an appropriate level of balance is equally as tricky as regaining it once balance has been lost. In the case of current economic standings with inflation on the rise and a slowing economy it's a question of which fire would be the most urgent one to fight. Raising rates could slow the economy and cause a recession, something they don't want; lowering it too much might cause inflation to raise exponentially, also not something favorable in the eyes of economists. Consideration in either case causes concern in the employment factor, the consumer factor is also at issue and then we must also consider how they interact within the economy. Mark Whitehouse reveals, in the piece done in the June 26, 2006 Wall Street Journal titled A Housing Slowdown Can Put the Brakes on a Job Sector but Open Other Opportunities, that the housing boom which our country has been enjoying may be coming to an end and this end makes the appearance of a bad thing. In actuality, the revelations found within this potentially devastating slowdown, could in fact bring about benefits at first unseen. "From a macroeconomic perspective, the housing slowdown, and the attendant slowing of job growth, could be just what the economy needs."1 In essence, the fact that houses are not selling as swiftly as they can be built or as swiftly as someone needs to be transferred may actually prove beneficial in other areas of the economic landscape. This change can further cause a rise in movement elsewhere within the macroeconomic landscape, continuing the cycle that will bring economic relief. Isabelle Lindenmayer writes about the state of the US dollar in her article Dollar is to Enter an Unsteady Week Ahead of Fed Move. As in most cases, the dollar will have its good days and bad days on the market in regard to value, and on occasion, the Fed can influence those good and bad days. In an analysis of expert opinions, two factors,
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